{"id":3281,"date":"2023-05-03T11:19:53","date_gmt":"2023-05-03T09:19:53","guid":{"rendered":"https:\/\/rythmologie.fr\/index\/?p=3281"},"modified":"2023-05-03T12:18:05","modified_gmt":"2023-05-03T10:18:05","slug":"newsletter-mai-2023-adaptive-versus-conventional-resynchronisation-therapy-in-patients-with-heart-failure","status":"publish","type":"post","link":"https:\/\/rythmologie.fr\/index\/newsletter-mai-2023-adaptive-versus-conventional-resynchronisation-therapy-in-patients-with-heart-failure\/","title":{"rendered":" Newsletter Mai 2023 &#8211; Adaptive versus ..."},"content":{"rendered":"<p>[vc_row][vc_column css=&#8221;.vc_custom_1663235123898{margin-top: 0px !important;border-top-width: 0px !important;background-color: rgba(255,255,255,0.1) !important;*background-color: rgb(255,255,255) !important;}&#8221;]<div id=\"ultimate-heading-286869e08fa19b37e\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-286869e08fa19b37e uvc-7651  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"center\" style=\"text-align:center\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-286869e08fa19b37e h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"--font-weight:theme;margin-top:20px;margin-bottom:20px;\">Newsletter Groupe Rythmologie \u2013 Stimulation cardiaque de la SFC<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-286869e08fa19b37e .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;margin-top:20px;margin-bottom:20px;\">Mai 2023<\/div><\/div>[vc_empty_space height=&#8221;24px&#8221;][vc_separator color=&#8221;custom&#8221; accent_color=&#8221;#e42925&#8243;][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"ultimate-heading-337769e08fa19b3d2\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-337769e08fa19b3d2 uvc-6360 \" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-337769e08fa19b3d2 h3'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"desktop:24px;\"}' ><h3 style=\"--font-weight:theme;color:#e42925;margin-top:24px;margin-bottom:24px;\">Adaptive versus conventional Resynchronisation therapy in patients with Heart failure<\/h3><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-337769e08fa19b3d2 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;color:#000000;margin-top:24px;margin-bottom:24px;\"><\/p>\n<div class=\"page\" title=\"Page 2\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<div class=\"page\" title=\"Page 4\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<div class=\"page\" title=\"Page 4\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p><em>Auteur :\u00a0<\/em><em>J\u00e9r\u00f4me TAIEB &#8211; Aix-en-Provence<\/em><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p><\/div><\/div>[vc_empty_space height=&#8221;24px&#8221;][vc_column_text]<\/p>\n<h3 style=\"font-weight: 400;\"><strong><u>But<\/u> :<\/strong><\/h3>\n<p style=\"font-weight: 400;\">D\u00e9montrer la sup\u00e9riorit\u00e9 de l\u2019algorithme dynamique Adaptive CRT de fusion stimulation VG avec la conduction native par rapport au mode CRT conventionnel chez les patients ayant une conduction AV pr\u00e9serv\u00e9e.<br \/>\nCrit\u00e8re primaire\u00a0: mortalit\u00e9 ou d\u00e9compensation cardiaque<\/p>\n<h3 style=\"font-weight: 400;\"><strong><u>M\u00e9thode<\/u>\u00a0: <\/strong><\/h3>\n<p style=\"font-weight: 400;\">Randomis\u00e9es multicentriques simple aveugle. 3617 patients 65 ans, NYHA 3-4 FE &lt; 35% RS\u00a0\u00a0 PR &lt; 200 ms BBG typique (crit\u00e8res de strauss) QRS &gt;140 ms (130 ms femme) Suivi 59 mois.<\/p>\n<h3 style=\"font-weight: 400;\"><strong><u>R\u00e9sultats<\/u>\u00a0:<\/strong><\/h3>\n<p style=\"font-weight: 400;\">Pas de diff\u00e9rences sur le crit\u00e8re primaire.<br \/>\nLes auteurs pr\u00e9cisent que les taux de mortalit\u00e9 sont plus bas que dans toutes les pr\u00e9c\u00e9dentes \u00e9tudes de resynchronisation.<br \/>\nIls montrent en posthoc qu\u2019un taux de fusion &gt;85% est associ\u00e9 \u00e0 une diminution de 24% de la mortalit\u00e9\/ d\u00e9compensation cardiaque.<br \/>\nIls pr\u00e9cisent que l\u2019\u00e9tude de longue dur\u00e9e a \u00e9t\u00e9 perturb\u00e9e par la p\u00e9riode COVID avec des retard de r\u00e9sultats qui aurait d\u00fb \u00e9viter l\u2019arr\u00eat pr\u00e9matur\u00e9.<\/p>\n<p style=\"font-weight: 400;\">Enfin ils notent un taux \u00e9lev\u00e9 de BBG typique qui peut expliquer le taux \u00e9lev\u00e9 de r\u00e9pondeurs dans le groupe CRT ce qui ne refl\u00e8te pas les populations habituelles.<\/p>\n<h3 style=\"font-weight: 400;\"><strong><u>Au total<\/u>\u00a0:\u00a0<\/strong><\/h3>\n<p style=\"font-weight: 400;\">\u00c9tude n\u00e9gative pour d\u00e9montrer la sup\u00e9riorit\u00e9 de l\u2019algorithme Adaptive CRT sur le CRT conventionnel. Les sous analyses laissent toutefois une place au concept de stimulation fusion qui apparait efficace lorsqu\u2019il est tr\u00e8s sollicit\u00e9 (&gt;85%).<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-3284 aligncenter\" src=\"https:\/\/rythmologie.fr\/index\/wp-content\/uploads\/2023\/05\/Capture-decran-2023-05-03-a-11.16.06-300x153.png\" alt=\"\" width=\"718\" height=\"366\" srcset=\"https:\/\/rythmologie.fr\/index\/wp-content\/uploads\/2023\/05\/Capture-decran-2023-05-03-a-11.16.06-300x153.png 300w, https:\/\/rythmologie.fr\/index\/wp-content\/uploads\/2023\/05\/Capture-decran-2023-05-03-a-11.16.06-1024x524.png 1024w, https:\/\/rythmologie.fr\/index\/wp-content\/uploads\/2023\/05\/Capture-decran-2023-05-03-a-11.16.06-768x393.png 768w, https:\/\/rythmologie.fr\/index\/wp-content\/uploads\/2023\/05\/Capture-decran-2023-05-03-a-11.16.06.png 1510w\" sizes=\"auto, (max-width: 718px) 100vw, 718px\" \/><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-3285 aligncenter\" src=\"https:\/\/rythmologie.fr\/index\/wp-content\/uploads\/2023\/05\/Capture-decran-2023-05-03-a-11.16.13-300x147.png\" alt=\"\" width=\"624\" height=\"306\" srcset=\"https:\/\/rythmologie.fr\/index\/wp-content\/uploads\/2023\/05\/Capture-decran-2023-05-03-a-11.16.13-300x147.png 300w, https:\/\/rythmologie.fr\/index\/wp-content\/uploads\/2023\/05\/Capture-decran-2023-05-03-a-11.16.13-1024x503.png 1024w, https:\/\/rythmologie.fr\/index\/wp-content\/uploads\/2023\/05\/Capture-decran-2023-05-03-a-11.16.13-768x377.png 768w, https:\/\/rythmologie.fr\/index\/wp-content\/uploads\/2023\/05\/Capture-decran-2023-05-03-a-11.16.13.png 1532w\" sizes=\"auto, (max-width: 624px) 100vw, 624px\" \/>[\/vc_column_text][vc_empty_space height=&#8221;24px&#8221;][vc_empty_space height=&#8221;24px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][vc_empty_space][vc_separator][vc_empty_space][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column css=&#8221;.vc_custom_1663235123898{margin-top: 0px !important;border-top-width: 0px !important;background-color: rgba(255,255,255,0.1) !important;*background-color: rgb(255,255,255) !important;}&#8221;][vc_empty_space height=&#8221;24px&#8221;][vc_separator color=&#8221;custom&#8221; accent_color=&#8221;#e42925&#8243;][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space height=&#8221;24px&#8221;][vc_column_text] But : D\u00e9montrer la sup\u00e9riorit\u00e9 de l\u2019algorithme dynamique Adaptive CRT de fusion stimulation VG avec la conduction native par rapport au mode CRT conventionnel chez les patients ayant une conduction AV pr\u00e9serv\u00e9e. Crit\u00e8re primaire\u00a0: mortalit\u00e9 ou d\u00e9compensation cardiaque M\u00e9thode\u00a0: Randomis\u00e9es multicentriques&hellip;<\/p>\n","protected":false},"author":2,"featured_media":3283,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[31,22],"tags":[],"class_list":["post-3281","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-newsletter","category-articles","category-31","category-22","description-off"],"_links":{"self":[{"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/posts\/3281","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/comments?post=3281"}],"version-history":[{"count":5,"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/posts\/3281\/revisions"}],"predecessor-version":[{"id":3312,"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/posts\/3281\/revisions\/3312"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/media\/3283"}],"wp:attachment":[{"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/media?parent=3281"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/categories?post=3281"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rythmologie.fr\/index\/wp-json\/wp\/v2\/tags?post=3281"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}